Promoted
Allevate - Ketamine Therapy Princeton
707 State Road, Suite 105, Princeton
5.0(10 Google reviews)
Offers SPRAVATO®
(609) 507-3890View profile →
Independent national directory · 550 cities
Find Spravato treatment near you
A national directory of certified Spravato (esketamine) treatment centers, with plain-language guides on cost, insurance, and what to expect.
2178
Verified US listings
48
States covered
REMS
Certified-setting treatment
2+ hrs
Monitoring after each dose
Provider directory
SPRAVATO® treatment centers across the United States
Compare clinic locations, insurance information, REMS certification status when verified, and direct contact details.
Promoted
Allevate - Ketamine Therapy Middletown
1270 New Jersey 35, Suite 4, Middletown Township
5.0(6 Google reviews)
Offers SPRAVATO®
(732) 302-8885View profile →
LifeStance Therapists & Psychiatrists Friendswood
308 South Friendswood Drive, Suite 200, Friendswood
4.8(5977 Google reviews)
Offers SPRAVATO®
(832) 219-3898View profile →
Denova Collaborative Health, Integrated Health Center
3033 North Central Avenue, Suite 700, Phoenix
4.8(2714 Google reviews)
Offers SPRAVATO®
(602) 281-7289View profile →
Access Pain Solutions | Tulsa Pain Management Doctor
4750 South Garnett Road, Tulsa
4.8(2667 Google reviews)
Offers SPRAVATO®
(918) 710-4112View profile →
Rochester Center for Behavioral Medicine
441 South Livernois Road, 100, Rochester Hills
4.7(1980 Google reviews)
Offers SPRAVATO®
(248) 608-8800View profile →
Getting started
How do I get started with SPRAVATO®?
Three steps, no referral needed in most cases. Here is what the path from searching to your first session actually looks like.
- 01
Find a treatment center near you
Search by city or ZIP and compare verified location, contact, insurance, and REMS details.
- 02
Book your consultation
Call the practice directly or send one short request and we pass it straight to clinics taking new patients.
- 03
Complete a clinical evaluation
A qualified healthcare professional determines whether SPRAVATO® is appropriate, reviews safety risks, and discusses an individualized schedule.
What SPRAVATO® is
A prescription esketamine nasal spray given only in certified healthcare settings
FDA-approved prescription medicine
SPRAVATO® is esketamine nasal spray. A healthcare professional supervises self-administration in a certified treatment setting.
Coverage requires individual verification
Coverage and prior-authorization rules vary by diagnosis, plan, benefit design, and treatment center. Confirm benefits before treatment.
Monitoring is required after every dose
The clinic monitors you for at least two hours after administration. You must arrange transportation and not drive until the next day after restful sleep.
By condition
The FDA-approved uses of SPRAVATO®
Our guides separate the two adult indications from broader depression education and explain important limitations.
Treatment-Resistant Depression (TRD)
SPRAVATO® (esketamine) nasal spray is FDA-approved for adults with treatment-resistant depression — depression that has not improved after at least two antidepressants, used alone or with an oral antidepressant.
Read moreMajor Depression with Suicidal Thoughts or Actions
SPRAVATO® is FDA-approved, together with an oral antidepressant, for adults with major depressive disorder who have acute suicidal ideation or behavior — as part of urgent, supervised care.
Read moreBrowse by location
Find SPRAVATO® treatment by state
Every visit requires in-clinic dosing, monitoring, and transportation home, so location matters.
Resource hub
Guides for United States patients
Insurance & cost
Which insurers cover SPRAVATO®? What major health plans ask for
Most large U.S. health plans publish a coverage policy for SPRAVATO®. Here is what those policies commonly require, and how to check your own plan.
September 28, 2026 · 5 min read
Understanding SPRAVATO®
What Is SPRAVATO® (Esketamine)? A Plain-English Guide
What SPRAVATO® is, the two adult uses the FDA has approved, and how it differs from a pill you take at home.
September 28, 2026 · 3 min read
Treatment journey
What Happens at a SPRAVATO® Treatment Visit
Before, during, and after a monitored treatment session — including the two-hour observation and why you need a ride home.
September 28, 2026 · 3 min read
Free, no obligation
Tell us where you are and we'll help you find a nearby treatment center
Share your town and your insurance. We match you with providers who treat your condition, accept your plan, and are actually taking new patients.
- No cost and no obligation
- We never sell your information
- Usually answered within one business day
News desk
SPRAVATO® news & updates
Insurance & cost
How Medicare Covers SPRAVATO® — and What to Ask Your Plan
SPRAVATO® is usually billed under Medicare Part B. Here is what original Medicare, Medicare Advantage, and Medigap can mean for your cost — and the questions to ask.
Treatment updates
What the Pivotal Esketamine Trials Showed — and What They Didn't
The TRANSFORM, SUSTAIN, and ASPIRE studies established SPRAVATO®'s approvals. Here is what the evidence supports — and where it stops.
Treatment updates
FDA Label Now Allows SPRAVATO® Alone for Treatment-Resistant Depression
The January 2025 prescribing information lists SPRAVATO® for adult TRD either as monotherapy or with an oral antidepressant.