Safety
Medical Disclaimer
Last updated 16 September 2026
Read this before acting on anything you find here.
If you are in crisis
Call or text 988 to reach the Suicide & Crisis Lifeline, 24 hours a day, or call 911 if you or someone else is in immediate danger. Do not wait for a clinic to call you back.
This is information, not advice
Esketamine Therapy publishes educational information about SPRAVATO® (esketamine) and a directory of treatment centers. Nothing on this site is medical advice, a diagnosis, a treatment recommendation, or a professional referral. Reading this site does not create a doctor-patient relationship with us or with any clinic listed here.
Only a qualified healthcare professional who has evaluated you can determine whether SPRAVATO® is appropriate and how it should fit with other care. Never stop, start or change a prescribed treatment based on something you read here.
FDA-approved uses and an important limitation
SPRAVATO® is FDA-approved for treatment-resistant depression in adults, as monotherapy or with an oral antidepressant, and for depressive symptoms in adults with major depressive disorder and acute suicidal ideation or behavior, together with an oral antidepressant. Effectiveness in preventing suicide or reducing suicidal ideation or behavior has not been demonstrated, and SPRAVATO® does not replace hospitalization when clinically warranted.
Results vary
Published trial results describe groups of people, not individuals. No clinic can promise you a particular outcome, and we do not publish success-rate claims that a clinic cannot substantiate. SPRAVATO® has boxed warnings for sedation, dissociation, respiratory depression, abuse and misuse, and suicidal thoughts and behaviors. It must be administered in a certified setting, followed by monitoring for at least two hours. Discuss your complete history and medicines with the treating clinician.
About our listings
Listing details are compiled from public sources, mapping data, and the clinics themselves. Insurance participation, availability, protocols, pricing and staffing change frequently. Verify everything directly with the clinic before booking or traveling. Inclusion in this directory is not an endorsement, a credential check, or a statement about quality of care. Exclusion means only that we have not verified the practice.
Editorial standards
Our articles cite primary sources — peer-reviewed studies, FDA labeling, official REMS materials, and published payer policies — and are reviewed for accuracy before publication. See our editorial policy. If you spot an error, please tell us and we will correct it.
